Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368972 | 1.00 | EPHX1 (0.52) | EPHX1CASP3ALDH1A1DPP4KCNH2 | |
| SCHEMBL14392696 | 1.00 | EPHX1 (0.52) | EPHX1CASP3ALDH1A1DPP4KCNH2 | |
| SCHEMBL14368638 | 1.00 | EPHX1 (0.52) | EPHX1CASP3ALDH1A1DPP4KCNH2 | |
| SCHEMBL26253804 | 0.84 | EPHX1 (0.57) | EPHX1CASP3ALDH1A1MEN1KMT2A | |
| SCHEMBL14368746 | 0.83 | EPHX2 (0.56) | ALDH1A1MEN1KMT2ACCR3 | |
| SCHEMBL28944413 | 0.83 | EPHX2 (0.56) | ALDH1A1MEN1KMT2ACCR3 | |
| SCHEMBL14392357 | 0.83 | EPHX1 (0.55) | EPHX1CASP3ALDH1A1MEN1KMT2A | |
| SCHEMBL19515030 | 0.83 | EPHX1 (0.55) | EPHX1CASP3ALDH1A1MEN1KMT2A | |
| SCHEMBL14368969 | 0.83 | EPHX1 (0.55) | EPHX1CASP3ALDH1A1MEN1KMT2A | |
| SCHEMBL3883687 | 0.83 | EPHX1 (0.55) | EPHX1CASP3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |