Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.50 |
| ▸ | CCR3 | P51677 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368746 | 1.00 | EPHX2 (0.56) | EPHX2SIGMAR1CCR3MEN1ALDH1A1 | |
| SCHEMBL14368730 | 0.88 | POLB (0.58) | SIGMAR1CCR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL28783273 | 0.88 | POLB (0.58) | SIGMAR1CCR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL27757306 | 0.87 | SIGMAR1 (0.55) | EPHX2SIGMAR1ALDH1A1GLS | |
| SCHEMBL14368710 | 0.87 | SIGMAR1 (0.55) | EPHX2SIGMAR1ALDH1A1GLS | |
| SCHEMBL14368687 | 0.84 | EPHX2 (0.60) | EPHX2SIGMAR1CCR3ALDH1A1NPC1 | |
| SCHEMBL14368806 | 0.83 | CCR3 (0.50) | CCR3ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL4429053 | 0.83 | CCR3 (0.50) | CCR3ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL14392696 | 0.83 | EPHX1 (0.52) | CCR3MEN1ALDH1A1KMT2A | |
| SCHEMBL14368972 | 0.83 | EPHX1 (0.52) | CCR3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |