Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541408 | 0.92 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541407 | 0.92 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Cadazolid SCHEMBL29379581 | 0.92 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Cadazolid SCHEMBL541681 | 0.92 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Cadazolid SCHEMBL541618 | 0.92 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21074700 | 0.90 | KDM4E (0.43) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL702285 | 0.89 | TOP2B (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29433777 | 0.89 | TOP2B (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541524 | 0.88 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541522 | 0.88 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535305-A | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-16 | — | — | CN | claimed |
| CN-101535305-B | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD | 2013-09-18 | — | — | CN | disclosed |
| CN-101535305-A | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-16 | — | — | CN | disclosed |