Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352221 | 0.85 | UGT2B7 (0.42) | CYP2D6 | |
| SCHEMBL858 | 0.79 | CYP2D6 (0.42) | CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10708013 | 0.77 | HTT (0.44) | CYP1A2CYP2D6TSHR | |
| SCHEMBL27607579 | 0.75 | CYP2A6 (0.44) | ALDH1A1HSD17B10CYP2A6TSHRMAPT | |
| Cyclopropane SCHEMBL28325005 | 0.74 | CYP2D6 (0.38) | HIF1ACYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL5537752 | 0.73 | IDO1 (0.58) | HIF1ACYP1A2CYP2D6TSHRMAPT | |
| SCHEMBL5536665 | 0.73 | IDO1 (0.45) | — | |
| SCHEMBL5545086 | 0.72 | ACP3 (0.46) | — | |
| SCHEMBL5541595 | 0.72 | IDO1 (0.60) | — | |
| Propane SCHEMBL28323919 | 0.72 | HTT (0.49) | ALDH1A1CYP1A2CYP2D6TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101583617-B | 4-(2-oxo-oxazolidin-3yl)-phenoxymethyle derivativeas as antibacterials | ACTELION PHARMACEUTICALS LTD | 2012-08-29 | — | — | CN | disclosed |
| CN-101583617-A | 4-(2-oxo-oxazolidin-3yl)-phenoxymethyle derivativeas as antibacterials | ACTELION PHARMACEUTICALS LTD (CH) | 2009-11-18 | — | — | CN | disclosed |