Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SCN1A | P35498 | 3/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL858 | 0.91 | CYP2D6 (0.42) | HTTLMNASCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL10708013 | 0.89 | HTT (0.44) | HTTLMNASCN1ASCN2ASCN3A | |
| Cyclopropane SCHEMBL28325005 | 0.85 | CYP2D6 (0.38) | HTTLMNASCN1ASCN2ASCN3A | |
| SCHEMBL5536665 | 0.80 | IDO1 (0.45) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL5537752 | 0.80 | IDO1 (0.58) | HTTLMNAADRA1ACYP1A2CHRM2 | |
| SCHEMBL468391 | 0.80 | HTT (0.35) | HTTLMNASCN1ASCN2ASCN3A | |
| SCHEMBL13616887 | 0.78 | LMNA (0.42) | HTTLMNACYP2D6SLC6A4KMT2A | |
| SCHEMBL1827511 | 0.78 | LMNA (0.42) | HTTLMNACYP2D6SLC6A4KMT2A | |
| SCHEMBL27586901 | 0.77 | HTT (0.37) | HTTLMNASCN1ASCN2ASCN3A | |
| SCHEMBL11352221 | 0.76 | UGT2B7 (0.42) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164072-B | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2019-10-01 | — | — | CN | disclosed |