Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.82 |
| ▸ | GAA | P10253 | 2/20 | 0.82 |
| ▸ | NT5E | P21589 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Verazide SCHEMBL564065 | 1.00 | MPO (0.82) | MPOGAANT5EALDH1A1KMT2A | |
| Ftivazide SCHEMBL436184 | 0.90 | GAA (1.00) | MPOGAANT5EALDH1A1KMT2A | |
| Verazide SCHEMBL679196 | 0.87 | MPO (0.63) | MPOGAANT5EALDH1A1KMT2A | |
| SCHEMBL19283306 | 0.86 | GAA (0.67) | MPOGAANT5EALDH1A1KMT2A | |
| SCHEMBL19283305 | 0.86 | GAA (0.67) | MPOGAANT5EALDH1A1KMT2A | |
| SCHEMBL12443618 | 0.83 | HTT (0.73) | MPOGAANT5EALDH1A1KMT2A | |
| SCHEMBL12443272 | 0.82 | ASF1A (0.70) | MPOGAANT5EALDH1A1KMT2A | |
| SCHEMBL21211567 | 0.82 | GAA (0.66) | MPOGAANT5EALDH1A1KMT2A | |
| SCHEMBL13381467 | 0.82 | MEN1 (0.88) | MPOGAANT5EALDH1A1KMT2A | |
| SCHEMBL11983864 | 0.81 | SMN1; SMN2 (0.64) | GAAALDH1A1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784274-A | The method and composition that suppresses edema factor and adenyl cyclase | MISSION PHARMA CO | 2010-07-21 | — | — | CN | disclosed |