Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513988 | 0.89 | MAPT (0.45) | LMNAMAPTMEN1KMT2ALTA4H | |
| SCHEMBL8211650 | 0.87 | CTNNB1 (0.54) | CTNNB1LMNAMAPTMEN1NR1I2 | |
| SCHEMBL11769161 | 0.84 | BID (0.51) | MAPTPPARABIDMCL1BCL2L1 | |
| SCHEMBL11773602 | 0.84 | BID (0.51) | MAPTPPARABIDMCL1BCL2L1 | |
| SCHEMBL6151348 | 0.84 | BID (0.51) | MAPTPPARABIDMCL1BCL2L1 | |
| SCHEMBL472738 | 0.84 | BID (0.51) | MAPTPPARABIDMCL1BCL2L1 | |
| SCHEMBL8368946 | 0.83 | PPARA (0.46) | LMNAMAPTMEN1NR1I2CHRM2 | |
| Hydrochloric Acid SCHEMBL7055004 | 0.81 | CTNNB1 (0.43) | CTNNB1LMNAMAPTMEN1NR1I2 | |
| Benzene SCHEMBL28299279 | 0.81 | KMT2A (0.51) | CTNNB1LMNAMAPTMEN1NR1I2 | |
| SCHEMBL1408037 | 0.80 | PPARA (0.53) | LMNAMAPTMEN1KMT2APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101613321-A | The list and the bicyclic pyrrole derivatives that suppress part and advanced glycation end product acceptor interaction | TRANSTECH PHARMA INC | 2009-12-30 | — | — | CN | disclosed |
| CN-101597262-A | The list and the bicyclic pyrrole derivatives that suppress part and advanced glycation end product acceptor interaction | TRANSTECH PHARMA INC (US) | 2009-12-09 | — | — | CN | disclosed |