Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665804 | 0.85 | USP30 (0.56) | — | |
| SCHEMBL3638888 | 0.81 | USP30 (0.54) | — | |
| SCHEMBL4938421 | 0.81 | USP30 (0.54) | — | |
| SCHEMBL7756336 | 0.79 | HDAC4 (0.51) | DRD4PKMMEN1KMT2ANPC1 | |
| SCHEMBL27808340 | 0.78 | PTAFR (0.47) | MCHR1 | |
| SCHEMBL27808373 | 0.77 | CRHR1 (0.40) | AURKAAURKBDRD4MEN1KMT2A | |
| SCHEMBL28787440 | 0.77 | CRHR1 (0.40) | AURKAAURKBDRD4MEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL28784363 | 0.75 | HDAC4 (0.41) | AURKAAURKBOPRK1NPC1RAB9A | |
| SCHEMBL8366923 | 0.71 | RECQL (0.60) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27759531 | 0.71 | USP30 (0.49) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778838-A | Azacyclylbenzamide derivatives as histamine-3 antagonists | WYETH CORP | 2010-07-14 | — | — | CN | disclosed |