Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407463 | 0.76 | TDP1 (0.40) | TDP1ALDH1A1NR1H4SORT1KDM4E | |
| SCHEMBL2878434 | 0.75 | TDP1 (0.39) | TDP1ALDH1A1NR1H4SORT1KDM4E | |
| SCHEMBL15004834 | 0.70 | TDP1 (0.50) | TDP1ALDH1A1NR1H4SORT1KDM4E | |
| SCHEMBL1356449 | 0.69 | TDP1 (0.71) | TDP1ALDH1A1NR1H4KDM4EHSD17B10 | |
| SCHEMBL29361914 | 0.69 | TDP1 (0.56) | TDP1ALDH1A1NR1H4SORT1KDM4E | |
| SCHEMBL105948 | 0.69 | TDP1 (0.56) | TDP1ALDH1A1NR1H4SORT1KDM4E | |
| SCHEMBL31528338 | 0.69 | TDP1 (0.71) | TDP1ALDH1A1NR1H4KDM4EHSD17B10 | |
| SCHEMBL29441322 | 0.69 | TDP1 (0.56) | TDP1ALDH1A1NR1H4SORT1KDM4E | |
| Water SCHEMBL28451483 | 0.68 | TDP1 (0.44) | TDP1ALDH1A1NR1H4SORT1KDM4E | |
| SCHEMBL1098811 | 0.68 | TDP1 (0.54) | TDP1ALDH1A1NR1H4SORT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |