Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 13/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964362 | 0.81 | PGK1 (0.40) | PTPN1 | |
| SCHEMBL9181306 | 0.76 | PTPN5 (0.42) | PTPN1 | |
| SCHEMBL8636351 | 0.76 | PTPN1 (0.47) | ALDH1A1PTPN1 | |
| SCHEMBL11735789 | 0.75 | PTPN1 (0.34) | TDP1ALDH1A1KDM4EHPGDPTPN1 | |
| SCHEMBL2878439 | 0.75 | TDP1 (0.40) | TDP1ALDH1A1SORT1KDM4EHPGD | |
| SCHEMBL4407463 | 0.75 | TDP1 (0.40) | TDP1ALDH1A1SORT1KDM4EHPGD | |
| SCHEMBL11249782 | 0.73 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL9862480 | 0.72 | CA1 (0.51) | TDP1ALDH1A1HPGDLMNA | |
| SCHEMBL11253983 | 0.72 | MEN1 (0.40) | ALDH1A1PTPN1LMNA | |
| SCHEMBL27685872 | 0.71 | PTPN1 (0.36) | CYP2C19PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |