SCHEMBL28786294

SCHEMBL28786294

CC(N)(COC(N)=O)c1nc(CO[Si](C)(C)C(C)(C)C)cs1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23416972 0.80 NPC1 (0.31) SMN1; SMN2
SCHEMBL23390042 0.79 SMN1; SMN2 (0.33) LMNAPKMSMN1; SMN2
SCHEMBL20681165 0.77 HRH1 (0.30)
SCHEMBL23416973 0.76 LATS1 (0.34) LMNA
SCHEMBL4902324 0.76 ALDH1A1 (0.38) LMNAHSD17B10PKMSMN1; SMN2
SCHEMBL21962248 0.76
Hydrochloric Acid SCHEMBL29519261 0.75 ALDH1A1 (0.37) HSD17B10PKMSMN1; SMN2
SCHEMBL21963406 0.73 NPC1 (0.31) SMN1; SMN2
SCHEMBL23416968 0.72
SCHEMBL15349137 0.72 MAPT (0.35) LMNAPKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114727987-A Substituted heterocyclic compounds having HIV therapeutic activity 纽约血库公司 2022-07-08 CN disclosed