SCHEMBL287865

SCHEMBL287865

CO[C@@H]([C@H](O)[C@H](O)CO)[C@@H](O)C=O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
AKR1B1 P15121 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MPI P34949 1/20 0.33
PDE4A P27815 1/20 0.33
TOP1 P11387 1/20 0.32
USP2 O75604 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1428140 1.00 LMNA (0.39) LMNAL3MBTL1TDP1MGAMSI
SCHEMBL2318762 1.00 LMNA (0.39) LMNAL3MBTL1TDP1MGAMSI
SCHEMBL8970781 1.00 LMNA (0.39) LMNAL3MBTL1TDP1MGAMSI
SCHEMBL557541 1.00 LMNA (0.39) LMNAL3MBTL1TDP1MGAMSI
SCHEMBL19859337 0.88 MPI (0.34) LMNAL3MBTL1MGAMSIMPI
SCHEMBL19859338 0.88 MPI (0.34) LMNAL3MBTL1MGAMSIMPI
SCHEMBL3142523 0.88 AKR1B1 (0.37) LMNAL3MBTL1AKR1B1MPI
SCHEMBL5453628 0.88 AKR1B1 (0.37) LMNAL3MBTL1AKR1B1MPI
SCHEMBL183626 0.88 AKR1B1 (0.37) LMNAL3MBTL1AKR1B1MPI
SCHEMBL5770928 0.88 AKR1B1 (0.37) LMNAL3MBTL1AKR1B1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3745856-B1 METHODS OF SUPERCOOLING AQUEOUS SAMPLES MASSACHUSETTS GEN HOSPITAL (US) 2025-11-19 EP claimed
US-12472475-B2 Methods of supercooling aqueous samples THE GENERAL HOSPITAL CORPORATION (US) 2025-11-18 US claimed
WO-2025217183-A1 PREPARED NATURAL KILLER CELLS AND USES THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-10-16 WO claimed
US-12239126-B2 Methods and compositions for preserving tissues and organs THE GENERAL HOSPITAL CORPORATION (US) 2025-03-04 US claimed
US-20240397936-A1 HIGH SUBZERO CRYOPRESERVATION THE GENERAL HOSPITAL CORPORATION 2024-12-05 US claimed
US-12115232-B2 Preparation for magnetic resonance diagnostics for oncological diseases, comprising deuterated 3-O-methylglucose, and diagnostic method using said preparation SOLVEX LIMITED LIABILITY COMPANY (RU) 2024-10-15 US claimed
EP-3557989-B1 ICE-FREE PRESERVATION OF LARGE VOLUME TISSUE SAMPLES FOR VIABLE, FUNCTIONAL TISSUE BANKING TISSUE TESTING TECH LLC (US) 2024-09-04 EP claimed
US-20240268372-A1 Methods and Compositions for Extending Organ and Tissue Preservation MASSACHUSETTS GEN HOSPITAL (US) 2024-08-15 US claimed
US-12058996-B2 High subzero cryopreservation THE GENERAL HOSPITAL CORPORATION (US) 2024-08-13 US claimed
CN-118063525-A Method for preparing triazole glucoside compound by one-pot method 国科大杭州高等研究院 2024-05-24 CN claimed
US-6562796-B2 Water-soluble, glycosyl derivatives of the antibiotic, e.g Amphotericin B, Nystatin A1; fungicides; nontoxic; prepared by the Amadori rearrangement reaction of a reducing sugar and the antibiotic MICROLOGIX BIOTECH INC. (CA) 2003-05-13 US claimed
US-20020035071-A1 Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites PROCTER & GAMBLE COMPANY, THE 2002-03-21 US claimed
WO-1999061482-A1 PRODUCTION OF CHITOSAN- AND CHITIN-LIKE EXOPOLYMERS TRUSTEES OF TUFTS COLLEGE (US) 1999-12-02 WO claimed
US-5756328-A PURE ENZYME WHICH CATALYZES TRANSFER OF ACYL SUBSTITUENTS TO PRODUCE SUGAR ESTERS OR SUGAR POLYESTERS, HAVING SPECIFIED AMINO ACID SEQUENCE CORNELL RESEARCH FOUNDATION, INC. (US) 1998-05-26 US claimed
EP-0590034-B1 METHOD FOR DETERMINING THE PRESENCE OF DIABETES ASSOCIATED ANTIBODIES OR ISLET CELL DIRECTED ANTIBODIES UNIV TEXAS (US) 1996-11-06 EP claimed
WO-1996028190-A1 NON-INVASIVE IMAGING OF GENE TRANSFER SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-09-19 WO claimed
WO-1992021979-A1 METHODS AND COMPOSITIONS RELATING TO GENETICALLY ENGINEERED CELLS THAT PRODUCE INSULIN IN RESPONSE TO GLUCOSE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-12-10 WO claimed
EP-0125039-B1 ENZYMATIC PRODUCTION OF PHOSPHOLIPID-SACCHARIDE DERIVATIVES MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 EP claimed
US-4624919-A Enzymatic production of phospholipid-saccharide derivatives MEITO SANGYO KABUSHIKI KAISHA (JP) 1986-11-25 US claimed
EP-0125039-A2 Enzymatic production of phospholipid-saccharide derivatives MEITO SANGYO KABUSHIKI KAISHA (JP) 1984-11-14 EP claimed