SCHEMBL2878717

SCHEMBL2878717

CCCCCCC(C)c1cc(N)ccc1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
SPHK1 Q9NYA1 2/20 0.38
CSNK1E P49674 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
OPRM1 P35372 1/20 0.35
SRC P12931 1/20 0.35
SKP2 Q13309 1/20 0.34
GRM2 Q14416 1/20 0.34
MAPT P10636 3/20 0.33
ADA P00813 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 2/20 0.33
POLB P06746 2/20 0.33
HTT P42858 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HTR2A P28223 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11538867 1.00 TSHR (0.38) TSHRSPHK1CSNK1EGPR84OPRM1
SCHEMBL27525500 0.98 OPRM1 (0.36) TSHRSPHK1CSNK1EGPR84OPRM1
SCHEMBL3955291 0.93 SKP2 (0.36) TSHRSRCSKP2GRM2MAPT
SCHEMBL7855771 0.87 TSHR (0.38) TSHRSPHK1CSNK1EGPR84OPRM1
SCHEMBL11810115 0.86 GAA (0.37) TSHRSKP2MAPTALDH1A1KDM4E
SCHEMBL28643126 0.83 PDE5A (0.40) GPR84OPRM1SRCSKP2ALDH1A1
SCHEMBL23929268 0.82 NR1I2 (0.40) TSHRSPHK1CSNK1ESRCSKP2
SCHEMBL9861405 0.80 SPHK2 (0.38) SPHK1MAPTHTR2AATMCYP2D6
SCHEMBL11440073 0.80 NR1I2 (0.38) TSHRSPHK1CSNK1EOPRM1SRC
SCHEMBL20921378 0.79 CYP1A2 (0.41) TSHRSPHK1CSNK1EOPRM1ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117203271-A Use of a stabilizer composition for stabilizing halogen-free thermoplastic recycling material, a stabilizer composition, a masterbatch or concentrate, a stabilized plastic composition, a method for stabilizing halogen-free thermoplastic recycling material and use of a composition 弗劳恩霍夫应用研究促进协会 2023-12-08 CN claimed
CN-114479187-B Low-smoke 70A asphalt and preparation method thereof 中国石油化工股份有限公司 2023-12-01 CN claimed
CN-110945066-B Halogen-free sulfonate and/or sulfinate esters as flame retardants, flame retardant synergists and free radical generators in plastics 弗劳恩霍弗应用研究促进协会 2022-10-14 CN claimed
CN-114479187-A Low-smoke 70A asphalt and preparation method thereof 中国石油化工股份有限公司 2022-05-13 CN claimed
EP-3658616-A1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2020-06-03 EP claimed
CN-110945066-A Halogen-free sulfonate and/or sulfinate esters as flame retardants, flame retardant synergists and free radical generators in plastics 弗劳恩霍弗应用研究促进协会 2020-03-31 CN claimed
CN-106232670-A Polyurethane foams based on polyether carbonate polyols 科思创德国股份有限公司 2016-12-14 CN claimed
CN-105669882-A Azonium-ionized poly(styrene-b-isobutylene-b-styrene) triblock copolymer and preparation method thereof 北京化工大学 2016-06-15 CN claimed
CN-104981509-A Process for recycling polymer composition waste comprising peroxide crosslinking agent PRYSMIAN SPA 2015-10-14 CN claimed
EP-1902106-A1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS Henkel Corporation (US) 2008-03-26 EP claimed
WO-2007008199-A1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS HENKEL CORPORATION (US) 2007-01-18 WO claimed
WO-2003078537-A2 CURE ACCELERATORS FOR ANAEROBIC ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2003-09-25 WO claimed
CN-1159131-A Electroluminescent devices BAYER AG (DE) 1997-09-10 CN claimed
EP-0539576-B1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME LUBRIZOL CORP (US) 1996-05-29 EP claimed
WO-1992020765-A1 DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO claimed
EP-4399102-A1 TYRE FOR VEHICLE WHEELS Pirelli Tyre S.p.A. (IT) 2024-07-17 EP disclosed
CN-118354911-A Motorcycle tyre 倍耐力轮胎股份公司 2024-07-16 CN disclosed
WO-1983004038-A1 POLYESTER COMPOSITION ETHYL CORPORATION (US) 1983-11-24 WO disclosed
US-4129607-A EPOXY RESIN, HYDROXY TERMINATED POLY(ETHER-ESTER) BLOCK COPOLYMER UNITECH CHEMICAL INC. (US) 1978-12-12 US disclosed
US-4113799-A BUTYL RUBBER, SELF-HEALING TIRES ROCKET RESEARCH CORP. (US) 1978-09-12 US disclosed