Toluene

Toluene

SCHEMBL28787236

Cc1ccccc1.O=S(=O)(Oc1ccccc1)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PPARG P37231 3/20 0.45
LMNA P02545 2/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
ACHE P22303 1/20 0.44
CXCR2 P25025 2/20 0.42
KMT2A Q03164 2/20 0.41
PTGS2 P35354 1/20 0.41
CXCR1 P25024 1/20 0.41
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
FFAR1 O14842 1/20 0.39
NFE2L2 Q16236 1/20 0.39
NR3C1 P04150 1/20 0.38
PGR P06401 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8821206 0.89 CA1 (0.56) CA1CA2CA9PPARGLMNA
SCHEMBL780030 0.89 CA1 (0.56) CA1CA2CA9PPARGLMNA
SCHEMBL2750188 0.88 CA2 (0.57) CA1CA2CA9HTTSMN1; SMN2
SCHEMBL27804335 0.87 CA1 (0.54) CA1CA2CA9PPARGLMNA
SCHEMBL6923665 0.87 CA1 (0.54) CA1CA2CA9PPARGLMNA
SCHEMBL1128833 0.87 CA1 (0.54) CA1CA2CA9PPARGLMNA
SCHEMBL28043817 0.87 CA1 (0.54) CA1CA2CA9PPARGLMNA
Methane SCHEMBL27573607 0.87 CA1 (0.54) CA1CA2CA9PPARGLMNA
SCHEMBL28807949 0.87 CA1 (0.54) CA1CA2CA9PPARGLMNA
Iodide SCHEMBL3347577 0.87 CA1 (0.54) CA1CA2CA9PPARGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101774871-A Method for preparing biaryl compound in pure water solution UNIV DALIAN TECH 2010-07-14 CN disclosed