Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | UNG | P13051 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480443 | 0.83 | AKR1C3 (0.47) | RXRARXRBAKR1C3KMONR4A2 | |
| SCHEMBL40750 | 0.83 | SLC7A5 (0.56) | RXRARXRBAKR1C3KMOALDH1A1 | |
| SCHEMBL30163785 | 0.83 | SLC7A5 (0.56) | RXRARXRBAKR1C3KMOALDH1A1 | |
| SCHEMBL4762259 | 0.81 | RXRA (0.46) | RXRARXRBAKR1C3KMOALDH1A1 | |
| SCHEMBL10716896 | 0.81 | UNG (0.41) | CYP2C19HIF1AALDH1A1ALOX15UNG | |
| Terephthalic Acid SCHEMBL11412636 | 0.80 | SLC7A5 (0.54) | RXRARXRBAKR1C3KMOALDH1A1 | |
| Ethylene SCHEMBL11411611 | 0.80 | SLC7A5 (0.54) | RXRARXRBAKR1C3KMOALDH1A1 | |
| Terephthalic Acid SCHEMBL11412970 | 0.77 | SLC7A5 (0.51) | RXRARXRBAKR1C3ALDH1A1NR4A1 | |
| SCHEMBL4734192 | 0.77 | NSD2 (0.54) | CYP2C19HIF1AALDH1A1ALOX15POLB | |
| Hydrogen Peroxide SCHEMBL27146001 | 0.77 | SLC7A5 (0.60) | CYP2C19ALDH1A1ALOX15CYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101760468-B | Halogenohydrin dehalogenase mutant strain, halogenohydrin dehalogenase mutant and preparation method and application thereof | ANGEL YEAST CO LTD | 2012-09-19 | — | — | CN | disclosed |
| CN-101760468-A | Halogenohydrin dehalogenase mutant strain, halogenohydrin dehalogenase mutant and preparation method and application thereof | ANGEL YEAST CO LTD | 2010-06-30 | — | — | CN | disclosed |