Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381732 | 0.95 | ECE1 (0.38) | SLC6A3MAPTHTR2BALDH1A1ECE1 | |
| SCHEMBL16398633 | 0.93 | ECE1 (0.40) | SLC6A3MAPTHTR2BALDH1A1ECE1 | |
| SCHEMBL9381967 | 0.89 | SLC6A3 (0.39) | SLC6A3MAPTHTR2BALDH1A1TLR8 | |
| SCHEMBL10771875 | 0.81 | — | — | |
| SCHEMBL21699960 | 0.73 | SLC6A3 (0.52) | SLC6A3ALDH1A1TLR8TLR7 | |
| SCHEMBL11570650 | 0.73 | SLC6A3 (0.42) | SLC6A3ALDH1A1TLR8TLR7ECE1 | |
| SCHEMBL5774433 | 0.73 | — | — | |
| SCHEMBL2435123 | 0.73 | MAPT (0.45) | MAPTHTR2BALDH1A1KDM4E | |
| SCHEMBL24075911 | 0.72 | MEN1 (0.40) | SLC6A3MAPTALDH1A1ECE1KDM4E | |
| SCHEMBL30665041 | 0.72 | SLC6A3 (0.51) | SLC6A3ALDH1A1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083839-A | Compound (I) | ASTRAZENECA AB | 2011-06-01 | — | — | CN | disclosed |