Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | PARP1 | P09874 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.61 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL9986816 | 0.94 | NAPRT (0.68) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| Benzamide SCHEMBL1679005 | 0.93 | CYP3A4 (0.76) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| Benzamide SCHEMBL1679183 | 0.91 | CYP3A4 (0.73) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| Pyridine SCHEMBL11103170 | 0.91 | CYP3A4 (0.58) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| Carbamic Acid SCHEMBL29194228 | 0.91 | NAPRT (0.61) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| SCHEMBL8582840 | 0.91 | NAPRT (0.59) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| SCHEMBL44995 | 0.91 | — | — | |
| Benzamide SCHEMBL10489522 | 0.90 | MAPT (0.64) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| SCHEMBL31228697 | 0.89 | CYP3A4 (0.70) | CYP3A4CYP2C19L3MBTL1POLBPARP1 | |
| Oxalic Acid SCHEMBL1648442 | 0.88 | NAPRT (0.58) | CYP3A4CYP2C19L3MBTL1POLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112476-A | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM INT | 2011-06-29 | — | — | CN | disclosed |