Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | PARP1 | P09874 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | F7 | P08709 | 1/20 | 0.63 |
| ▸ | F3 | P13726 | 1/20 | 0.63 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.63 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228697 | 0.98 | CYP3A4 (0.70) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL27937969 | 0.94 | CYP3A4 (0.64) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL1679005 | 0.93 | CYP3A4 (0.76) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Pyridine SCHEMBL11103170 | 0.91 | CYP3A4 (0.58) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL28787993 | 0.91 | CYP3A4 (0.73) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL27841146 | 0.89 | CYP3A4 (0.70) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL28132124 | 0.85 | PARP1 (0.89) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL3870712 | 0.85 | PARP1 (0.89) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL8632915 | 0.85 | PARP1 (0.89) | CYP3A4CYP2C19POLBPARP1MAPT | |
| Benzamide SCHEMBL6690447 | 0.85 | PARP1 (1.00) | CYP3A4CYP2C19POLBPARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735850-A | Synthesis method of 1,2, 4-triazole compound | 河南师范大学 | 2021-12-03 | — | — | CN | claimed |
| CN-106831285-A | The method that acid amides, urea are converted into ester | 湖北科技学院 | 2017-06-13 | — | — | CN | claimed |
| CN-104860308-B | A kind of method that application combustion synthesis method prepares nitrogen-doped graphene | 哈尔滨工业大学 | 2017-05-31 | — | — | CN | claimed |
| CN-101917856-A | Combinations comprising a fungicidal strain and an active compound | BASF SE | 2010-12-15 | — | — | CN | claimed |
| CN-120157555-A | Preparation method of primary amide compound | 浙江工业大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-113735850-A | Synthesis method of 1,2, 4-triazole compound | 河南师范大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113735850-A | Synthesis method of 1,2, 4-triazole compound | 河南师范大学 | 2021-12-03 | — | — | CN | disclosed |
| WO-2021018165-A1 | PYRIDINE BENZAMIDE DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICINAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2021-02-04 | — | — | WO | disclosed |
| WO-2021018165-A1 | PYRIDINE BENZAMIDE DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICINAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2021-02-04 | — | — | WO | disclosed |
| CN-107573950-B | A kind of aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal display element | 中节能万润股份有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-109593089-A | The preparation of diaza spiro decane piperidine formyl amine compound and application | 西南大学 | 2019-04-09 | — | — | CN | disclosed |
| CN-108367000-A | THERAPEUTIC AGENT FOR BREAST CANCER | 卫材R&D管理有限公司 | 2018-08-03 | — | — | CN | disclosed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | disclosed |
| EP-0912516-A4 | ANTICONVULSANT PYRIDINYL BENZAMIDE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-0912516-A1 | ANTICONVULSANT PYRIDINYL BENZAMIDE DERIVATIVES | Bristol-Myers Squibb Company (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5859033-A | Anticonvulsant pyridinyl benzamide derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997043261-A1 | ANTICONVULSANT PYRIDINYL BENZAMIDE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-11-20 | — | — | WO | disclosed |
| US-5550122-A | INHIBIT REVERSE TRANSCRIPTASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0415303-B1 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMA (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0415303-A2 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1991-03-06 | — | — | EP | disclosed |