Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587335 | 0.88 | PRKDC (0.48) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL21404002 | 0.88 | GRIN2D (0.45) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL29663687 | 0.88 | GRIN2D (0.45) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL2125933 | 0.86 | GAA (0.50) | TAAR1POLBL3MBTL1MAPTNPSR1 | |
| SCHEMBL263749 | 0.86 | NPC1 (0.56) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL19709407 | 0.86 | GAA (0.50) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL29885672 | 0.86 | NPC1 (0.56) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL298224 | 0.84 | POLB (0.59) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL30888547 | 0.83 | POLB (0.54) | HTR2ATAAR1HTR2CPOLBL3MBTL1 | |
| SCHEMBL19404754 | 0.82 | NQO2 (0.44) | HTR2ATAAR1HTR2CPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751921-A | Non-condensed ring receptor molecule based on chlorophenyl-central nucleus and application thereof | 西安交通大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114751921-A | Non-condensed ring receptor molecule based on chlorophenyl-central nucleus and application thereof | 西安交通大学 | 2022-07-15 | — | — | CN | disclosed |