SCHEMBL2879014

SCHEMBL2879014

c1ccc(Oc2cccc(-c3cccc(Oc4ccccc4)c3)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.63
TSHR P16473 1/20 0.63
MAOB P27338 1/20 0.60
GSTP1 P09211 1/20 0.56
AKR1C3 P42330 1/20 0.54
FFAR1 O14842 1/20 0.53
FFAR4 Q5NUL3 1/20 0.53
GAA P10253 3/20 0.50
MEN1 O00255 1/20 0.50
MITF O75030 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
GFER P55789 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NLRP1 Q9C000 1/20 0.50
NOD2 Q9HC29 1/20 0.50
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
MAOA P21397 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11817160 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL11816136 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL4536542 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL11820920 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL9461749 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL11817552 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL11816748 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL11821068 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL11816430 0.97 LTA4H (0.60) LTA4HTSHRMAOBGSTP1AKR1C3
SCHEMBL11818460 0.95 MEN1 (0.58) LTA4HTSHRMAOBGSTP1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754844-B2 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-07-13 US disclosed
EP-1561768-B1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE TOYO BOSEKI (JP) 2009-09-30 EP disclosed
US-20060166048-A1 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2006-07-27 US disclosed
EP-1561768-A1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE Toyo Boseki Kabushiki Kaisha (JP) 2005-08-10 EP disclosed