Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 15/20 | 0.56 |
| ▸ | JAK1 | P23458 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046592 | 0.86 | ZAP70 (0.61) | ZAP70JAK1JAK2 | |
| SCHEMBL13752982 | 0.86 | ZAP70 (0.50) | ZAP70JAK1JAK2FER | |
| SCHEMBL1048813 | 0.86 | ZAP70 (0.56) | ZAP70JAK1JAK2FER | |
| SCHEMBL1048131 | 0.86 | ZAP70 (0.56) | ZAP70JAK1JAK2FERTYK2 | |
| SCHEMBL1047313 | 0.85 | ZAP70 (0.51) | ZAP70JAK1JAK2FER | |
| SCHEMBL3358977 | 0.85 | ZAP70 (0.51) | ZAP70JAK1JAK2FERTYK2 | |
| SCHEMBL13752853 | 0.85 | ZAP70 (0.51) | ZAP70JAK1JAK2FER | |
| SCHEMBL1048068 | 0.84 | ZAP70 (0.54) | ZAP70JAK1JAK2 | |
| SCHEMBL1158014 | 0.84 | ZAP70 (0.66) | ZAP70JAK2 | |
| SCHEMBL1047828 | 0.84 | ZAP70 (0.54) | ZAP70JAK1JAK2FER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101990539-A | Compounds and compositions as kinase inhibitors | IRM LLC | 2011-03-23 | — | — | CN | disclosed |