SCHEMBL287905

SCHEMBL287905

[CH2]C(C)(C)NC(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 2/20 0.36
TGFBR1 P36897 1/20 0.34
KDM4E B2RXH2 1/20 0.33
RXFP1 Q9HBX9 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138082 0.81 EPHX1 (0.41) TDP1ALDH1A1TGFBR1KDM4ERXFP1
SCHEMBL9242168 0.79 EPHX1 (0.39) TDP1ALDH1A1TGFBR1KDM4ERXFP1
SCHEMBL11122559 0.79 ALDH1A1 (0.36) TDP1ALDH1A1TGFBR1KDM4ERXFP1
SCHEMBL822811 0.79 ALDH1A1 (0.36) TDP1ALDH1A1TGFBR1KDM4ERXFP1
SCHEMBL1032432 0.79 ALDH1A1 (0.36) TDP1ALDH1A1TGFBR1KDM4ERXFP1
SCHEMBL7709808 0.77 TDP1 (0.39) TDP1ALDH1A1TGFBR1KDM4ERXFP1
SCHEMBL12322278 0.77 ALDH1A1 (0.35) TDP1ALDH1A1TGFBR1KDM4ERXFP1
Dimethylamine SCHEMBL27557791 0.77 EPHX1 (0.38) TDP1ALDH1A1TGFBR1KDM4ERXFP1
SCHEMBL829187 0.76 ALDH1A1 (0.38) TDP1ALDH1A1TGFBR1KDM4ERXFP1
Hydrochloric Acid SCHEMBL11184246 0.75 TDP1 (0.38) TDP1ALDH1A1TGFBR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338635-B1 Method for controlling corrosion using molybdate compositions CALGON CORP (US) 1995-12-27 EP claimed
EP-2427466-A1 PROCESS FOR PRODUCING A PARTICULATE NANOCOMPOSITE MATERIAL BASF SE (DE) 2012-03-14 EP disclosed
WO-2010128144-A1 PROCESS FOR PRODUCING A PARTICULATE NANOCOMPOSITE MATERIAL BASF SE (DE) 2010-11-11 WO disclosed