Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27826229 | 0.90 | IGF1R (0.57) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27845191 | 0.90 | IGF1R (0.57) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27826235 | 0.90 | IGF1R (0.54) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27940499 | 0.88 | IGF1R (0.54) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27826192 | 0.86 | IGF1R (0.53) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27845189 | 0.86 | IGF1R (0.53) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27845382 | 0.84 | IGF1R (0.53) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27845205 | 0.84 | IGF1R (0.53) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL28790506 | 0.83 | IGF1R (0.60) | IGF1RADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL27826227 | 0.83 | ALDH1A1 (0.53) | IGF1RADRB2ADRB1ADRB3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101985438-A | Substituted phenyl piperazinyl aralkylone derivatives and application thereof to preparation of analgesics | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2011-03-16 | — | — | CN | claimed |
| CN-101985438-A | Substituted phenyl piperazinyl aralkylone derivatives and application thereof to preparation of analgesics | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2011-03-16 | — | — | CN | disclosed |