Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827973 | 0.81 | MAPT (0.41) | CA1CA2ALDH1A1CA12CA9 | |
| SCHEMBL1806672 | 0.80 | CA1 (0.46) | PTGES2CA1CA2CA12CA9 | |
| SCHEMBL25852925 | 0.78 | MEN1 (0.44) | CA1CA2ALDH1A1L3MBTL1CYP2C19 | |
| SCHEMBL1806670 | 0.78 | PTGES2 (0.44) | PTGES2CA1CA2CA12CA9 | |
| SCHEMBL1807035 | 0.77 | PTGES2 (0.44) | PTGES2CA1CA2ALDH1A1L3MBTL1 | |
| SCHEMBL30485967 | 0.76 | PYCR1 (0.44) | ALDH1A1CYP2D6CYP2C19MEN1LMNA | |
| SCHEMBL22122719 | 0.76 | PYCR1 (0.44) | ALDH1A1CYP2D6CYP2C19MEN1LMNA | |
| SCHEMBL157921 | 0.75 | IDO1 (0.50) | L3MBTL1CYP2C19CYP3A4IDO1 | |
| SCHEMBL29712851 | 0.75 | IDO1 (0.50) | L3MBTL1CYP2C19CYP3A4IDO1 | |
| SCHEMBL1807032 | 0.75 | PTGES2 (0.45) | PTGES2CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102050766-B | Synthesis method for amosulalol hydrochloride | ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD | 2013-08-07 | — | — | CN | disclosed |
| CN-102050766-A | Synthesis method for amosulalol hydrochloride | ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD | 2011-05-11 | — | — | CN | disclosed |