Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24738322 | 0.73 | HTR2A (0.53) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL2916068 | 0.73 | HTR2A (0.53) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL1347107 | 0.70 | SLC6A3 (0.63) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL1347104 | 0.70 | SLC6A3 (0.63) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL1347110 | 0.70 | SLC6A3 (0.63) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL1349834 | 0.70 | SLC6A3 (0.51) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL1349149 | 0.70 | SLC6A3 (0.51) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL1349152 | 0.70 | SLC6A3 (0.51) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL27909987 | 0.70 | HDAC2 (0.45) | HDAC2MAPT | |
| SCHEMBL19995526 | 0.70 | HDAC2 (0.45) | HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056902-B | Imidazolidine derivatives | HOFFMANN LA ROCHE | 2013-08-07 | — | — | CN | disclosed |
| CN-102056902-A | Imidazolidine derivatives | HOFFMANN LA ROCHE | 2011-05-11 | — | — | CN | disclosed |