Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644833 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRCYP3A4RECQL | |
| SCHEMBL11695700 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRCYP3A4POLB | |
| SCHEMBL28061957 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRCYP3A4POLB | |
| SCHEMBL27898207 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRCYP3A4HPGD | |
| SCHEMBL27338694 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRPOLBHPGD | |
| SCHEMBL8501106 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRCYP3A4RECQL | |
| SCHEMBL28194935 | 0.78 | MAPK14 (0.47) | ALDH1A1TDP1TSHRMAPT | |
| SCHEMBL11453634 | 0.78 | MAPT (0.49) | ALDH1A1TSHRCYP3A4RECQLPOLB | |
| SCHEMBL28226522 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRPOLBHPGD | |
| SCHEMBL14269307 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRCYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102050814-B | Ester derivatives of dabigatran | BEIJING MEIBEITA PHARMACEUTICAL RES INST CO LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-102050815-B | Dabigatran ester derivatives as prodrug | BEIJING MEIBEITA PHARMACEUTICAL RES CO LTD | 2014-04-02 | — | — | CN | disclosed |
| CN-103420980-A | Dabigatran derivatives | BEIJING MEIBEITA DRUG RES CO LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-102050815-A | Dabigatran ester derivatives as prodrug | BEIJING MEIBEITA PHARMACEUTICAL RES INST CO LTD | 2011-05-11 | — | — | CN | disclosed |
| CN-102050814-A | Ester derivatives of dabigatran | BEIJING MEIBEITA PHARMACEUTICAL RES INST CO LTD | 2011-05-11 | — | — | CN | disclosed |