Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809535 | 0.79 | MAPT (0.39) | MAPTHPGDHTTNPSR1GFER | |
| SCHEMBL27809528 | 0.76 | NMT1 (0.42) | MAPTHPGDKMT2ALMNASMN1; SMN2 | |
| SCHEMBL27809628 | 0.74 | TDP1 (0.46) | MAPTHPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL12608050 | 0.73 | CHUK (0.46) | MAPTMC4RHPGDHTTNPSR1 | |
| SCHEMBL27829946 | 0.69 | MAPT (0.53) | MAPTHPGDHTTNPSR1GFER | |
| SCHEMBL14422265 | 0.68 | HDAC1 (0.43) | MAPTGAAKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12605590 | 0.67 | PTGDR2 (0.40) | KMT2A | |
| SCHEMBL5213833 | 0.65 | KDM4E (0.43) | KMT2ALMNAMEN1KDM4E | |
| SCHEMBL12606721 | 0.65 | HTT (0.51) | MAPTHPGDHTTNPSR1MGAM | |
| SCHEMBL6269206 | 0.64 | MAPT (0.61) | MAPTHPGDHTTNPSR1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980664-B | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS | 2011-02-23 | — | — | CN | disclosed |