SCHEMBL5213833

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5219307	0.83	SLC6A2 (0.42)	TSHRTDP1PTGER1CCNA2CDK2
	SCHEMBL14422265	0.78	HDAC1 (0.43)	TDP1LMNAMEN1KMT2A
	SCHEMBL11910638	0.78	CES1 (0.50)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL14422264	0.76	SMN1; SMN2 (0.47)	KDM4ETDP1LMNA
	SCHEMBL14422204	0.75	TRPV1 (0.46)	RORCLMNA
	SCHEMBL1811036	0.73	CES1 (0.38)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL13685198	0.72	IGFBP3 (0.39)	PTGER1CES1
	SCHEMBL742811	0.71	CES1 (0.39)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL1707161	0.71	LMNA (0.43)	PTGER1CES1MRGPRX4KLKB1LMNA
	SCHEMBL2868442	0.70	NOTUM (0.46)	KDM4EALOX15TSHRACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.