SCHEMBL28792118

SCHEMBL28792118

COC(=O)c1c(Br)ccc(Br)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 3/20 0.40
CYP3A4 P08684 2/20 0.40
ACHE P22303 1/20 0.40
MEN1 O00255 1/20 0.40
NR4A2 P43354 1/20 0.40
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GRM6 O15303 1/20 0.39
GRM5 P41594 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29683902 1.00 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL11137262 0.88 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL15814236 0.86 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL1335275 0.86 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL23089733 0.85 TSHR (0.44) CA12CA1CA2CA7CA9
SCHEMBL31024688 0.85 LMNA (0.43) CA12CA1CA2CA7CA9
SCHEMBL21621671 0.85 LMNA (0.43) CA12CA1CA2CA7CA9
SCHEMBL22833407 0.85 TSHR (0.44) CA12CA1CA2CA7CA9
SCHEMBL1335494 0.85 GRM6 (0.42) CA12CA1CA2CA7CA9
SCHEMBL543319 0.85 GRM6 (0.42) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642689-B 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof 南通大学 2022-06-24 CN claimed
CN-110642689-A 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof 南通大学 2020-01-03 CN claimed
CN-110642689-B 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof 南通大学 2022-06-24 CN disclosed
CN-110642689-A 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof 南通大学 2020-01-03 CN disclosed