Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468780 | 0.80 | OGA (0.44) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL27756983 | 0.78 | HRH3 (0.61) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL3468795 | 0.78 | RAB9A (0.44) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3468783 | 0.77 | HRH3 (0.59) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3469499 | 0.74 | RAB9A (0.55) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL14403537 | 0.74 | NPC1 (0.51) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3468716 | 0.72 | NPC1 (0.56) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL3468608 | 0.71 | HRH3 (0.41) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3468828 | 0.71 | DPP4 (0.46) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3468880 | 0.71 | OGA (0.44) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410385-B | Benzothiazoles having histamine H3 receptor activity | HIGH POINT PHARMACEUTICALS LLC | 2011-08-24 | — | — | CN | claimed |