Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17304623 | 0.92 | SLC6A3 (0.58) | SLC6A3MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL17304622 | 0.88 | KMT2A (0.67) | SLC6A3MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL17304618 | 0.87 | MAPT (0.55) | SLC6A3MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL20110389 | 0.87 | MAPT (0.55) | SLC6A3MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL25270974 | 0.85 | MAPT (0.53) | SLC6A3MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL17304624 | 0.85 | MAPT (0.53) | SLC6A3MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL2877331 | 0.85 | SLC6A3 (0.69) | SLC6A3MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL27375218 | 0.84 | SLC6A3 (0.68) | SLC6A3MAPTKDM4EMAPK1KMT2A | |
| SCHEMBL2946505 | 0.84 | SLC6A3 (0.68) | SLC6A3MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL5695895 | 0.84 | SLC6A3 (0.72) | SLC6A3MAPTKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043866-A2 | HISTONE LYSINE DEMETHYLASE INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2010-04-22 | — | — | WO | disclosed |