Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27830627 | 0.95 | DRD2 (0.39) | TYRDRD2DRD4DRD3DRD1 | |
| SCHEMBL27830618 | 0.95 | DRD2 (0.39) | TYRDRD2DRD4DRD3DRD1 | |
| SCHEMBL27830620 | 0.88 | CNR2 (0.38) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL27852238 | 0.74 | DRD2 (0.33) | DRD2DRD4DRD3HSD17B1 | |
| SCHEMBL2934963 | 0.72 | TYR (0.41) | TYRMAOACNR1CNR2MEN1 | |
| SCHEMBL27830666 | 0.70 | HSP90AA1 (0.36) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL27578537 | 0.68 | ESR1 (0.56) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL27849144 | 0.68 | ESR1 (0.56) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL2935573 | 0.68 | MEN1 (0.43) | TYRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2932666 | 0.68 | MEN1 (0.43) | TYRMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101917989-A | Preparation containing chromane-2-one derivatives | MERCK PATENT GMBH | 2010-12-15 | — | — | CN | disclosed |