Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 4/20 | 0.36 |
| ▸ | ATP4B | P51164 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850904 | 0.90 | HTR1A (0.40) | HTR1AHTR7MEN1KMT2AATP4A | |
| SCHEMBL1778249 | 0.87 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL27850908 | 0.82 | CYP1A2 (0.42) | MEN1KMT2AMAPK1NPC1RAB9A | |
| SCHEMBL27850907 | 0.82 | AAK1 (0.39) | HTR1AHTR7MEN1KMT2AATP4A | |
| SCHEMBL27832553 | 0.78 | HTT (0.38) | HTR1AHTR7ATP4AATP4BALDH1A1 | |
| SCHEMBL27850909 | 0.77 | HTR1A (0.35) | HTR1AHTR7ATP4AATP4BUSP2 | |
| SCHEMBL1777276 | 0.76 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL1777047 | 0.76 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL27832555 | 0.75 | MEN1 (0.39) | HTR1AHTR7MEN1KMT2AATP4A | |
| SCHEMBL27850910 | 0.74 | MAPK1 (0.36) | HTR1AHTR7MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379049-B | Novel benzamidine derivatives, process for preparing the same, and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD | 2012-01-04 | — | — | CN | disclosed |