Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 1.00 |
| ▸ | CLK1 | P49759 | 2/20 | 0.80 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.80 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | CASP1 | P29466 | 1/20 | 0.73 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.73 |
| ▸ | CASP7 | P55210 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060304 | 1.00 | FLT3 (1.00) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL244128 | 0.91 | FLT3 (0.83) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL29431747 | 0.86 | FLT3 (0.76) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL648526 | 0.86 | FLT3 (0.76) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL10508628 | 0.86 | FLT3 (0.76) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL3379125 | 0.86 | CLK1 (0.82) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL9989803 | 0.85 | FLT3 (0.73) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL1390692 | 0.85 | KDM4E (1.00) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL30402838 | 0.85 | KDM4E (1.00) | FLT3CLK1DYRK1ADYRK1BKDM4E | |
| SCHEMBL31060274 | 0.84 | FLT3 (1.00) | FLT3CLK1DYRK1ADYRK1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186833-A | MIF modulators | UNIV YALE | 2011-09-14 | — | — | CN | disclosed |