Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | CASP1 | P29466 | 1/20 | 0.69 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.69 |
| ▸ | CASP7 | P55210 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | CLK1 | P49759 | 2/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.65 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795137 | 0.85 | FLT3 (1.00) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL31060304 | 0.85 | FLT3 (1.00) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL29431747 | 0.83 | FLT3 (0.76) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL10508628 | 0.83 | FLT3 (0.76) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL648526 | 0.83 | FLT3 (0.76) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL30402838 | 0.81 | KDM4E (1.00) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL3613922 | 0.81 | MAOB (0.63) | FLT3KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1390692 | 0.81 | KDM4E (1.00) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL23875930 | 0.80 | NPC1 (0.47) | FLT3KDM4EALDH1A1LMNAGLA | |
| SCHEMBL3619989 | 0.80 | PIM1 (0.72) | FLT3KDM4EALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |