Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.69 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.69 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964841 | 0.93 | S1PR1 (0.81) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL1966678 | 0.91 | S1PR1 (0.77) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL1965049 | 0.89 | S1PR1 (0.73) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL27856172 | 0.85 | S1PR1 (0.74) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL27838325 | 0.85 | S1PR1 (0.58) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL1966681 | 0.85 | S1PR1 (0.69) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL1966424 | 0.84 | S1PR1 (0.80) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL1647943 | 0.83 | S1PR1 (0.70) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL27838353 | 0.82 | S1PR1 (0.54) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL1966070 | 0.82 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186847-A | novel 2-amido thiadiazole derivatives | ALMIRALL SA | 2011-09-14 | — | — | CN | disclosed |