⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617135 | 0.98 | EPHX1 (0.60) | — | |
| SCHEMBL689158 | 0.92 | — | — | |
| SCHEMBL687717 | 0.81 | — | — | |
| SCHEMBL462123 | 0.79 | EPHX2 (0.55) | — | |
| SCHEMBL11594414 | 0.77 | EPHX1 (0.58) | — | |
| SCHEMBL11596219 | 0.77 | EPHX1 (0.58) | — | |
| SCHEMBL11594937 | 0.77 | EPHX1 (0.58) | — | |
| SCHEMBL11410599 | 0.77 | EPHX1 (0.58) | — | |
| SCHEMBL11595110 | 0.77 | EPHX1 (0.58) | — | |
| SCHEMBL11593203 | 0.77 | EPHX1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012793-A1 | FUNGICIDE AMINOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-02-04 | — | — | WO | claimed |
| EP-0000640-B1 | TETRAHYDRO-S-TRIAZINE THIONES, PROCESS FOR THEIR PREPARATION AND ACARICIDAL COMPOSITIONS CONTAINING THEM. | Pfizer Limited (GB) | 1981-06-03 | — | — | EP | claimed |
| EP-0000640-A1 | Tetrahydro-s-triazine thiones, process for their preparation and acaricidal compositions containing them. | Pfizer Limited (GB) | 1979-02-07 | — | — | EP | claimed |
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2010-03-25 | — | — | US | disclosed |
| WO-2010012793-A1 | FUNGICIDE AMINOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-02-04 | — | — | WO | disclosed |
| EP-2089395-A2 | NEW ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UnibioScreen S.A. (BE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008043846-A2 | NEW ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2008-04-17 | — | — | WO | disclosed |
| EP-1130017-B1 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMA CO LTD (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-RE37979-E1 | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | MITSUBISHI CHEMICAL CORPORATION | 2003-02-04 | — | — | US | disclosed |
| EP-0829476-B1 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | MITSUBISHI CHEM CORP (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-0934937-B1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMA CO LTD (JP) | 2002-02-27 | — | — | EP | disclosed |
| EP-0829476-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5677319-A | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5643932-A | PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5461060-A | Antiretroviral activity | MITSUBISHI KASEI CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0513387-A1 | ACTIVE OXYGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |
| EP-0420763-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0000640-B1 | TETRAHYDRO-S-TRIAZINE THIONES, PROCESS FOR THEIR PREPARATION AND ACARICIDAL COMPOSITIONS CONTAINING THEM. | Pfizer Limited (GB) | 1981-06-03 | — | — | EP | disclosed |
| EP-0000640-A1 | Tetrahydro-s-triazine thiones, process for their preparation and acaricidal compositions containing them. | Pfizer Limited (GB) | 1979-02-07 | — | — | EP | disclosed |
| EP-0000640-A1 | Tetrahydro-s-triazine thiones, process for their preparation and acaricidal compositions containing them. | Pfizer Limited (GB) | 1979-02-07 | — | — | EP | disclosed |