Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497506 | 0.92 | CYP3A4 (0.47) | HDAC2HDAC1HSD17B10CYP3A4USP2 | |
| SCHEMBL17411226 | 0.92 | CYP3A4 (0.47) | HDAC2HDAC1HSD17B10CYP3A4USP2 | |
| SCHEMBL22954519 | 0.90 | HDAC2 (0.52) | HDAC2HDAC1HSD17B10CYP3A4USP2 | |
| SCHEMBL26495720 | 0.90 | EGLN2 (0.45) | HDAC2HDAC1ALDH1A1LMNAMAPT | |
| SCHEMBL24793976 | 0.87 | HDAC2 (0.52) | HDAC2HDAC1HSD17B10CYP3A4USP2 | |
| SCHEMBL29709632 | 0.87 | HDAC2 (0.52) | HDAC2HDAC1HSD17B10CYP3A4USP2 | |
| SCHEMBL1707770 | 0.86 | MAPT (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL28945679 | 0.83 | ALDH1A1 (0.54) | HDAC2HDAC1HSD17B10CYP3A4USP2 | |
| SCHEMBL12004996 | 0.83 | CYP3A4 (0.55) | HDAC2HDAC1HSD17B10CYP3A4USP2 | |
| SCHEMBL17411219 | 0.83 | HDAC2 (0.46) | HDAC2HDAC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | disclosed |