Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 18/20 | 0.66 |
| ▸ | BRD4 | O60885 | 8/20 | 0.64 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945711 | 0.85 | EZH2 (0.64) | EZH2BRD4BRD2BRD3BRDT | |
| SCHEMBL28795561 | 0.78 | EZH2 (1.00) | EZH2BRD4BRD2BRD3BRDT | |
| SCHEMBL28795531 | 0.70 | EZH2 (1.00) | EZH2BRD4BRD2BRD3BRDT | |
| SCHEMBL17754070 | 0.68 | TAF1 (0.60) | EZH2BRD4 | |
| SCHEMBL17753694 | 0.68 | TAF1 (0.60) | EZH2BRD4 | |
| SCHEMBL17749030 | 0.67 | TAF1 (0.61) | EZH2BRD4 | |
| SCHEMBL28795470 | 0.66 | EZH2 (1.00) | EZH2BRD4BRD2BRD3BRDT | |
| SCHEMBL30615188 | 0.63 | EZH2 (1.00) | EZH2BRD4BRD2BRD3BRDT | |
| SCHEMBL28795497 | 0.63 | EZH2 (1.00) | EZH2BRD4BRD2BRD3BRDT | |
| SCHEMBL30073318 | 0.62 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805350-A | Benzo-heterocycle-pyridone derivatives and preparation method and application thereof | 四川大学华西医院 | 2022-07-29 | — | — | CN | disclosed |