Ethylene

Ethylene

SCHEMBL28796155

C=C.CC(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
MAPK1 P28482 1/20 0.52
HIF1A Q16665 1/20 0.52
GSR P00390 1/20 0.50
FOLH1 Q04609 1/20 0.49
OTC P00480 1/20 0.49
NOS2 P35228 5/20 0.49
NOS1 P29475 4/20 0.49
NOS3 P29474 3/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
PAOX Q6QHF9 2/20 0.48
BLM P54132 1/20 0.47
ADRA1A P35348 1/20 0.47
DPP7 Q9UHL4 1/20 0.46
MEN1 O00255 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
ARG1 P05089 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236178 0.96 KDM4E (0.56) KDM4EMAPK1HIF1AGSRFOLH1
SCHEMBL180969 0.96 KDM4E (0.56) KDM4EMAPK1HIF1AGSRFOLH1
SCHEMBL919222 0.96 KDM4E (0.56) KDM4EMAPK1HIF1AGSRFOLH1
SCHEMBL30125060 0.95 KDM4E (0.59) KDM4EMAPK1HIF1AGSRFOLH1
Hydrochloric Acid SCHEMBL28854969 0.95 KDM4E (0.54) KDM4EMAPK1HIF1AGSRFOLH1
Hydrochloric Acid SCHEMBL15669798 0.95 KDM4E (0.54) KDM4EMAPK1HIF1AGSRFOLH1
SCHEMBL3503365 0.91 OTC (0.57) KDM4EMAPK1HIF1AGSROTC
SCHEMBL976174 0.91 OTC (0.57) KDM4EMAPK1HIF1AGSROTC
SCHEMBL2238055 0.91 OTC (0.57) KDM4EMAPK1HIF1AGSROTC
Lysine SCHEMBL18825683 0.90 GSR (0.67) KDM4EMAPK1HIF1AGSRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102375065-A Identifying Method For Acylation Of Lysine Butane In Protein And Preparation Of Affine Reagent Thereof PTM BIOLAB INC 2012-03-14 CN disclosed