SCHEMBL976174

SCHEMBL976174

CC(=O)NCCC[C@H](N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.57
KDM4E B2RXH2 1/20 0.52
MAPK1 P28482 1/20 0.52
HIF1A Q16665 1/20 0.52
NOS2 P35228 5/20 0.50
NOS1 P29475 4/20 0.50
NOS3 P29474 3/20 0.50
GSR P00390 1/20 0.50
MEN1 O00255 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 1/20 0.50
DDAH1 O94760 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
PAOX Q6QHF9 2/20 0.48
BLM P54132 1/20 0.47
ADRA1A P35348 1/20 0.47
DPP7 Q9UHL4 1/20 0.46
ARG1 P05089 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3503365 1.00 OTC (0.57) OTCKDM4EMAPK1HIF1ANOS2
SCHEMBL2238055 1.00 OTC (0.57) OTCKDM4EMAPK1HIF1ANOS2
SCHEMBL236178 0.94 KDM4E (0.56) OTCKDM4EMAPK1HIF1ANOS2
SCHEMBL180969 0.94 KDM4E (0.56) OTCKDM4EMAPK1HIF1ANOS2
SCHEMBL919222 0.94 KDM4E (0.56) OTCKDM4EMAPK1HIF1ANOS2
Hydrochloric Acid SCHEMBL15669798 0.92 KDM4E (0.54) OTCKDM4EMAPK1HIF1ANOS2
SCHEMBL30125060 0.92 KDM4E (0.59) OTCKDM4EMAPK1HIF1ANOS2
Hydrochloric Acid SCHEMBL28854969 0.92 KDM4E (0.54) OTCKDM4EMAPK1HIF1ANOS2
Ethylene SCHEMBL28796155 0.91 KDM4E (0.52) OTCKDM4EMAPK1HIF1ANOS2
Lysine SCHEMBL20898428 0.88 GSR (0.67) OTCKDM4EMAPK1HIF1ANOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260009800-A1 METHODS OF DIAGNOSIS AND GUIDING TREATMENT OF VULVOVAGINAL SYMPTOMS AND FEMALE SEXUAL DYSFUNCTION UNIV ARIZONA (US) 2026-01-08 US claimed
WO-2025100520-A1 PEPTIDE, PEPTIDE COMPLEX, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR CELL CULTURE, AND COMPOSITION FOR MEDICAL USE, DIAGNOSTIC USE, OR RESEARCH USE ペプチドリーム株式会社 2025-05-15 WO claimed
EP-4482852-A1 PEPTIDIC INHIBITORS OF AMYLOID SELF- AND CROSS-ASSEMBLY Technische Universität München (DE) 2025-01-01 EP claimed
WO-2023161211-A1 PEPTIDIC INHIBITORS OF AMYLOID SELF- AND CROSS-ASSEMBLY Technische Universität München (DE) 2023-08-31 WO claimed
EP-4230645-A1 PEPTIDIC INHIBITORS OF AMYLOID SELF- AND CROSS-ASSEMBLY Technische Universität München (DE) 2023-08-23 EP claimed
US-20220402983-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH, INC. 2022-12-22 US claimed
CN-115279782-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2022-11-01 CN claimed
WO-2022080385-A1 PEPTIDE, AND MODIFICATION OF ANTIBODY WITH PEPTIDE 国立大学法人京都大学 2022-04-21 WO claimed
EP-3805756-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT Metabolon, Inc. (US) 2021-04-14 EP claimed
EP-3129909-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT Metabolon, Inc. (US) 2017-02-15 EP claimed
WO-2015157407-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT METABOLON, INC. (US) 2015-10-15 WO claimed
EP-2036918-A1 PEPTIDE DERIVATIVE Vexon, Inc. (JP) 2009-03-18 EP claimed
US-20080009448-A1 Peptide Derivative VEXON, INC. (50%) (JP) 2008-01-10 US claimed
EP-0749429-B1 3,5-DISUBSTITUTED AND 3,5,6-TRISUBSTITUTED 2-ISOXAZOLINES AND ISOXAZOLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS HOECHST AG (DE) 1999-06-30 EP claimed
US-20260146106-A1 BIFUNCTIONAL DEGRADERS OF GALACTOSE-DEFICIENT IMMUNOGLOBULINS BIOHAVEN THERAPEUTICS LTD. (US) 2026-05-28 US disclosed
EP-3808347-B1 SUBSTANCES FOR TREATMENT OF FATTY LIVER-RELATED CONDITIONS SCANDIBIO THERAPEUTICS AB (SE) 2026-05-20 EP disclosed
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH UNIV CALIFORNIA (US) 2026-03-19 US disclosed
US-6121479-A ANTIINFLAMMATORY AND ANTICARCINOGENIC AGENTS; AUTOIMMUNE DISEASES HOECHST AKTIENGESELLSCHAFT (DE) 2000-09-19 US disclosed
US-6060071-A Ectoin and ectoin derivatives as moisturizers in cosmetics MERCK PATENT GMBH (DE) 2000-05-09 US disclosed
US-5814627-A ANTIINFLAMMATORY AGENTS, ASTHMA; RHEUMATIC AND AUTOIMMUNE DISEASES; INHIBITORS OF LEUKOTRIENES, CYTOKINES, E.G. INTERLEUKINS, OXYGEN RADICALS AND PROTEASES HOECHST AKTIENEGESELLSCHAFT (DE) 1998-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402983-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP OTC 4590/4885KDM4E 4705/4885MAPK1 944/4885
US-20260146106-A1 BIFUNCTIONAL DEGRADERS OF GALACTOSE-DEFICIENT IMMUNOGLOBULINS ASGR1, FCGR2A, FCGR3B OTC 4646/4885KDM4E 3325/4885MAPK1 3168/4885
US-20260009800-A1 METHODS OF DIAGNOSIS AND GUIDING TREATMENT OF VULVOVAGINAL SYMPTOMS AND FEMALE SEXUAL DYSFUNCTION SHBG, GNRHR, STIM2 OTC 4651/4885KDM4E 3955/4885MAPK1 3656/4885
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH IDO1, INMT, IDO2 OTC 1197/4885KDM4E 553/4885MAPK1 3444/4885
US-20080009448-A1 Peptide Derivative ARGLU1, NGLY1, NPR3 OTC 4586/4885KDM4E 619/4885MAPK1 414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.