Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796241 | 0.75 | PTPN1 (0.75) | PTPN1 | |
| SCHEMBL7188203 | 0.75 | PTPN1 (0.68) | PTPN1 | |
| SCHEMBL7188190 | 0.75 | PTPN1 (0.68) | PTPN1 | |
| SCHEMBL806897 | 0.75 | CYP3A4 (0.38) | PTPN1ALOX5GABRA1CNR2GABRB2 | |
| SCHEMBL15978363 | 0.73 | CNR2 (0.34) | PTPN1ALOX5GABRA1CNR2GABRB2 | |
| SCHEMBL29415497 | 0.73 | ALDH1A1 (0.55) | ALOX5GABRA1CNR2GABRB2CYP3A4 | |
| SCHEMBL942820 | 0.73 | ALDH1A1 (0.55) | ALOX5GABRA1CNR2GABRB2CYP3A4 | |
| SCHEMBL28045599 | 0.72 | MAPT (0.48) | ALOX5GABRA1CNR2GABRB2CYP3A4 | |
| SCHEMBL5373419 | 0.71 | MAPT (0.37) | PTPN1ALOX5ALDH1A1KDM4EMEN1 | |
| SCHEMBL806744 | 0.71 | KDM4E (0.38) | PTPN1ALOX5GABRA1CNR2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503351-B | Chalcone derivative containing allyl structure and application thereof | 温州医科大学 | 2022-01-04 | — | — | CN | disclosed |