⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871889 | 0.81 | TSHR (0.43) | — | |
| SCHEMBL2022397 | 0.78 | DGAT1 (0.44) | — | |
| SCHEMBL17574065 | 0.78 | DGAT1 (0.44) | — | |
| SCHEMBL9207406 | 0.77 | — | — | |
| SCHEMBL5403225 | 0.77 | — | — | |
| SCHEMBL10961843 | 0.77 | CYP4F2 (0.40) | — | |
| Iodide SCHEMBL6295803 | 0.77 | TSHR (0.36) | — | |
| Bromide SCHEMBL6291576 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL47401 | 0.76 | — | — | |
| SCHEMBL17574066 | 0.76 | DGAT1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| CN-118339281-A | Engineered enzymes and methods of making and using the same | 基因组股份公司 | 2024-07-12 | — | — | CN | disclosed |
| US-11473110-B2 | Xylitol producing Metschnikowia species | Creatus Biosciences Inc. (CA) | 2022-10-18 | — | — | US | disclosed |
| US-11208673-B2 | Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid | GENOMATICA, INC. (US) | 2021-12-28 | — | — | US | disclosed |
| US-20210079334-A1 | FERMENTATION SYSTEMS AND METHODS WITH SUBSTANTIALLY UNIFORM VOLUMETRIC UPTAKE RATE OF A REACTIVE GASEOUS COMPONENT | AGAIN BIO APS (DK) | 2021-03-18 | — | — | US | disclosed |
| US-20200239915-A1 | XYLITOL PRODUCING METSCHNIKOWIA SPECIES | CREATUS BIOSCIENCES INC (CA) | 2020-07-30 | — | — | US | disclosed |
| US-20190330670-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2019-10-31 | — | — | US | disclosed |
| US-10150977-B2 | Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid | GENOMATICA, INC. (US) | 2018-12-11 | — | — | US | disclosed |
| US-20180195093-A1 | METSCHNIKOWIA SPECIES FOR BIOSYNTHESIS OF COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2018-07-12 | — | — | US | disclosed |
| US-20170218414-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2017-08-03 | — | — | US | disclosed |
| EP-1560834-B1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | disclosed |
| US-20060116363-A1 | Tricyclic derivatives as ltd4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-01 | — | — | US | disclosed |
| EP-1560834-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | Almirall Prodesfarma, S.A. (ES) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004043966-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-05-27 | — | — | WO | disclosed |
| EP-0480708-B1 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1995-10-11 | — | — | EP | disclosed |
| US-5266568-A | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-11-30 | — | — | US | disclosed |
| EP-0480708-A2 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |
| EP-0051284-B1 | NOVEL THIAPROSTAGLANDIN E1 DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1985-01-09 | — | — | EP | disclosed |
| US-4466980-A | Thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-08-21 | — | — | US | disclosed |
| EP-0051284-A1 | Novel thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceuticals containing these compounds | TEIJIN LIMITED (JP) | 1982-05-12 | — | — | EP | disclosed |