Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29749639 | 1.00 | NPC1 (0.50) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL23388043 | 0.88 | NPC1 (0.42) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL29749517 | 0.88 | NPC1 (0.42) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL19127703 | 0.87 | NPC1 (0.51) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL19715580 | 0.76 | KDM4C (0.41) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL21591631 | 0.75 | NPC1 (0.52) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL6400712 | 0.75 | NPC1 (0.59) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL25282359 | 0.74 | NPC1 (0.50) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL20524326 | 0.74 | KDM4C (0.45) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL23387990 | 0.73 | NPC1 (0.40) | NPC1RAB9AKDM4CL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114667286-A | Triazatricycles for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2022-06-24 | — | — | CN | disclosed |