SCHEMBL28796573

SCHEMBL28796573

ClC=CCOCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
IDO1 P14902 1/20 0.46
ALOX5 P09917 1/20 0.46
AGXT P21549 1/20 0.45
TK1 P04183 1/20 0.42
ALDH1A1 P00352 1/20 0.39
MAOB P27338 1/20 0.39
CA1 P00915 4/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
TACR1 P25103 2/20 0.38
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1524101 0.87 TSHR (0.67) TSHRIDO1ALOX5AGXTTK1
SCHEMBL1524098 0.87 TSHR (0.67) TSHRIDO1ALOX5AGXTTK1
SCHEMBL1524411 0.87 TSHR (0.67) TSHRIDO1ALOX5AGXTTK1
Ammonia Solution, Strong SCHEMBL7095980 0.85 TSHR (0.64) TSHRIDO1ALOX5AGXTTK1
SCHEMBL10532118 0.83 TSHR (0.61) TSHRIDO1ALOX5AGXTALDH1A1
SCHEMBL18321179 0.82 TSHR (0.54) TSHRIDO1ALOX5AGXTTK1
SCHEMBL641214 0.79 TSHR (0.56) TSHRIDO1ALOX5AGXTTK1
SCHEMBL3805959 0.79 TSHR (0.56) TSHRIDO1ALOX5AGXTTK1
SCHEMBL8125435 0.79 TSHR (0.56) TSHRIDO1ALOX5AGXTTK1
SCHEMBL10515956 0.79 TSHR (0.56) TSHRIDO1ALOX5AGXTTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103396350-A Method for synthesizing vitamin A from cis-1-halo-2-chloroolefine UNIV ZHEJIANG NORMAL 2013-11-20 CN disclosed
CN-102531830-A Cis-1-halo-2-chloroolefine and its preparation method and use UNIV ZHEJIANG NORMAL 2012-07-04 CN disclosed