Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TK1 | P04183 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524098 | 0.98 | TSHR (0.67) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL1524411 | 0.98 | TSHR (0.67) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL1524101 | 0.98 | TSHR (0.67) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL641214 | 0.89 | TSHR (0.56) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL8125435 | 0.89 | TSHR (0.56) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL641213 | 0.89 | TSHR (0.56) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL292313 | 0.87 | TSHR (0.54) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL12763795 | 0.87 | TSHR (0.54) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL2436225 | 0.87 | TSHR (0.54) | TSHRIDO1AGXTALOX5TK1 | |
| SCHEMBL2433172 | 0.87 | TSHR (0.54) | TSHRIDO1AGXTALOX5TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171610-A1 | Catalyst asymmetric desymmetrization of prochiral compounds | DENG LI (US) | 2003-09-11 | — | — | US | claimed |
| EP-1268368-A2 | CATALYTIC ASYMMETRIC DESYMMETRIZATION OF MESO COMPOUNDS | Brandeis University (US) | 2003-01-02 | — | — | EP | claimed |
| US-20020038048-A1 | Catalytic asymmetric desymmetrization of meso compounds | BRANDEIS UNIVERSITY | 2002-03-28 | — | — | US | claimed |
| WO-2001074741-A2 | CATALYTIC ASYMMETRIC DESYMMETRIZATION OF MESO COMPOUNDS | BRANDEIS UNIVERSITY (US) | 2001-10-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038048-A1 | Catalytic asymmetric desymmetrization of meso compounds | DNPH1, HDHD5, GNE | TSHR 4572/4885IDO1 430/4885AGXT 79/4885 |
| US-20030171610-A1 | Catalyst asymmetric desymmetrization of prochiral compounds | HPSE, HPD, APEH | TSHR 4334/4885IDO1 988/4885AGXT 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.