Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 6/20 | 0.53 |
| ▸ | KDR | P35968 | 6/20 | 0.52 |
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | TEK | Q02763 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.46 |
| ▸ | KIT | P10721 | 4/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | FGR | P09769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501287 | 0.84 | RET (0.60) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL22435918 | 0.75 | FGFR2 (0.62) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL20782714 | 0.75 | FGFR2 (0.51) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL20775123 | 0.74 | FGFR2 (0.57) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL24028631 | 0.73 | KDR (0.53) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL19957133 | 0.72 | FGFR4 (0.52) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL20775124 | 0.72 | FGFR2 (0.55) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL25466495 | 0.71 | FGFR2 (0.60) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL22435917 | 0.71 | KDR (0.57) | FGFR2KDRAURKAMETTEK | |
| SCHEMBL20782518 | 0.70 | FGFR2 (0.53) | FGFR2KDRAURKAMETTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892536-B | Substituted quinoline carboxamides and their use | 北京福元医药股份有限公司 | 2022-06-28 | — | — | CN | disclosed |