Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27849130 | 0.91 | PTGDR2 (0.50) | PTGDR2RORCCYP2C19 | |
| SCHEMBL27849048 | 0.86 | PTGDR2 (0.52) | PTGDR2RORC | |
| SCHEMBL27849064 | 0.81 | PTGDR2 (0.56) | PTGDR2RORC | |
| SCHEMBL27866134 | 0.79 | PTGDR2 (0.47) | PTGDR2PPARACYP2C19 | |
| SCHEMBL27849057 | 0.74 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL2657038 | 0.74 | PTGS2 (0.42) | PTGDR2 | |
| SCHEMBL1331607 | 0.73 | PTGDR2 (0.48) | PTGDR2PPARAPPARDPPARGRORC | |
| SCHEMBL27866130 | 0.72 | PTGDR2 (0.45) | PTGDR2PPARAPPARGRORC | |
| SCHEMBL28797001 | 0.71 | PTGDR2 (0.46) | PTGDR2PPARAPPARD | |
| SCHEMBL1333681 | 0.70 | PTGDR2 (0.59) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102557971-A | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-07-11 | — | — | CN | claimed |
| CN-101014564-B | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-05-09 | — | — | CN | claimed |
| CN-102557971-A | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-07-11 | — | — | CN | disclosed |
| CN-101014564-B | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-05-09 | — | — | CN | disclosed |