⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21797560 | 0.82 | — | — | |
| SCHEMBL18040915 | 0.82 | — | — | |
| SCHEMBL21724862 | 0.82 | — | — | |
| SCHEMBL22991077 | 0.78 | CHRNB2 (0.41) | — | |
| SCHEMBL28026274 | 0.78 | ATM (0.30) | — | |
| SCHEMBL20564607 | 0.77 | — | — | |
| SCHEMBL15536112 | 0.76 | HCRTR1 (0.32) | — | |
| SCHEMBL24828065 | 0.74 | USP2 (0.42) | — | |
| SCHEMBL758818 | 0.74 | USP2 (0.42) | — | |
| SCHEMBL20766180 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427450-A1 | GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| EP-2427448-A1 | Gpr 119 modulators | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128414-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128425-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |