Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 17/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20681386 | 0.97 | NLRP3 (0.53) | NLRP3ATMSMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL30120801 | 0.97 | NLRP3 (0.53) | NLRP3ATMSMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL21810595 | 0.90 | NLRP3 (0.44) | NLRP3 | |
| SCHEMBL21963025 | 0.86 | NLRP3 (0.48) | NLRP3ATMSMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL20681303 | 0.85 | NLRP3 (0.43) | NLRP3ATMSMN1; SMN2CA2 | |
| SCHEMBL30843786 | 0.85 | NLRP3 (0.43) | NLRP3ATMSMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL20703153 | 0.84 | NLRP3 (0.72) | NLRP3ALDH1A1 | |
| SCHEMBL29804891 | 0.83 | NLRP3 (0.61) | NLRP3ATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL23647905 | 0.82 | NLRP3 (0.41) | NLRP3ATMSMN1; SMN2CA2 | |
| SCHEMBL25034210 | 0.81 | NLRP3 (0.53) | NLRP3ATMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829345-A | Acylsulfonamide compound and medicinal use thereof | 日本烟草产业株式会社 | 2022-07-29 | — | — | CN | disclosed |